Prime IV Hydration & Wellness Hits 426% Growth in Latest Inc. 5000
With a 426% revenue surge over the past three years, Colorado Springs-based Prime IV Hydration & Wellness has secured the No. 809 spot on the 2026 Inc. 5000 list. This marks the third consecutive year the IV therapy franchise has earned a place among the fastest-growing independent businesses in the United States.

The ranking highlights a period of rapid expansion for the brand, which now operates in more than 200 communities nationwide. Founder and CEO Amy Neary attributes the company's sustained trajectory to the performance of its franchise owners and a rising consumer appetite for proactive, medically guided wellness services. The company currently provides a range of treatments including micronutrient injections and NAD+ therapy, catering to clients seeking support for athletic recovery, immune health, and cognitive function.
To qualify for the Inc. 5000, companies must demonstrate significant revenue growth, maintain independence, and meet strict financial thresholds, including a minimum revenue of $2 million by the end of 2025. Prime IV’s inclusion in the list follows its consistent recognition by industry publications, including a three-year streak as the top-ranked IV therapy franchise in Entrepreneur’s Franchise 500. The company plans to celebrate these results alongside other honorees at the upcoming Inc. 5000 Conference & Gala in Dallas this October.
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