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Plopii Debuts Paraxanthine Pouches as Caffeine Alternative

Brooklyn-based biotech startup Plopii has introduced a line of nicotine-free pouches designed to deliver sustained cognitive clarity. By utilizing paraxanthine—the primary metabolite of caffeine—the company aims to provide the benefits of traditional stimulants while avoiding the typical post-caffeine jitters, anxiety, and sleep disruption.

Bio & NewsJune 29, 2026912 reads0

Each pouch contains 120mg of paraxanthine, effectively bypassing the body’s metabolic conversion process to offer a more predictable energy profile. To further sharpen cognitive performance, the formula incorporates a blend of 60mg of Alpha-GPC, 60mg of Citicoline, and 60mg of L-theanine. Co-founder and CEO Michael Tolmach described the product as a solution for those seeking the efficacy of caffeine without the accompanying physiological costs.

Designed for creators and athletes, the pouches are available in five varieties: Cool Mint, Wintergreen, Tropical Mango, Blueberry, and Watermelon. The company is positioning these as both a nicotine-free alternative for pouch users and a cleaner, more manageable energy source for daily consumers. The product line is currently available through Amazon, TikTok Shop, and the company’s official website.

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